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Descriptor English: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Descriptor Spanish: 1-(5-Isoquinolinesulfonil)-2-Metilpiperazina
Descriptor 1-(5-isoquinolinesulfonil)-2-metilpiperacina
Entry term(s) H-7
Scope note: Inhibidor específico de la proteína cinasa C, que inhibe la liberación de superóxido de los neutrófilos humanos (PMN) estimulados con acetato de forbol miristato o diacilglicerol sintético.
Descriptor Portuguese: 1-(5-Isoquinolinasulfonil)-2-Metilpiperazina
Descriptor French: 5-(2-Méthyl-pipérazine-1-sulfonyl)isoquinoléine
Entry term(s): 1-(Isoquinoléine-5-sulfonyl)-2-méthyl-pipérazine
1-(Isoquinoléine-5-sulfonyl)-2-méthylpipérazine
5-(2-Méthylpipérazine-1-sulfonyl)isoquinoléine
H-7
Tree number(s): D02.886.590.700.545
D03.383.606.527
D03.633.100.531.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019307
Scope note: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Enzyme Inhibitors
Registry Number: 84477-87-2
CAS Type 1 Name: Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, (2S-(1(R*(R*)), 2alpha, 3abeta, 7abeta))-
DeCS ID: 32992
Unique ID: D019307
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2017/04/10
5-(2-Méthyl-pipérazine-1-sulfonyl)isoquinoléine - Preferred
Concept UI M0028749
Preferred term 5-(2-Méthyl-pipérazine-1-sulfonyl)isoquinoléine
Entry term(s) 1-(Isoquinoléine-5-sulfonyl)-2-méthyl-pipérazine
1-(Isoquinoléine-5-sulfonyl)-2-méthylpipérazine
5-(2-Méthylpipérazine-1-sulfonyl)isoquinoléine
H-7



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