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Descriptor English: Topotecan
Descriptor Spanish: Topotecan
Descriptor topotecan
Scope note: Agente antineoplásico utilizado para tratar el cáncer de ovario. Actúa inhibiendo las TOPOISOMERASAS DE ADN, TIPO I.
Descriptor Portuguese: Topotecan
Descriptor French: Topotécane
Entry term(s): 9-(Diméthylamino)méthyl-10-hydroxy-camptothécine
9-Diméthylaminométhyl-10-hydroxycamptothécine
Chlorhydrate de nogitécan
Chlorhydrate de topotécane
Hycamtamine
NSC-609699
NSC609699
SK&F-104864-A
SK&F104864 A
SK&F104864A
SKF-104864-A
Tree number(s): D03.132.151.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019772
Scope note: An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Topoisomerase I Inhibitors
Registry Number: 7M7YKX2N15
DeCS ID: 33404
Unique ID: D019772
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2017/01/17
Topotécane - Preferred
Concept UI M0029340
Preferred term Topotécane
Entry term(s) 9-(Diméthylamino)méthyl-10-hydroxy-camptothécine
9-Diméthylaminométhyl-10-hydroxycamptothécine
Hycamtamine
Chlorhydrate de topotécane - Narrower
Concept UI M0329084
Preferred term Chlorhydrate de topotécane
Entry term(s) Chlorhydrate de nogitécan
SK&F-104864-A - Narrower
Concept UI M0352761
Preferred term SK&F-104864-A
Entry term(s) SK&F104864 A
SK&F104864A
SKF-104864-A
NSC-609699 - Narrower
Concept UI M0352658
Preferred term NSC-609699
Entry term(s) NSC609699



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