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Descriptor English: Riluzole
Descriptor Spanish: Riluzol
Descriptor riluzol
Scope note: Antagonista del glutamato (RECEPTORES, GLUTAMATO) que se utiliza como anticonvulsivante y que prolonga la vida de los pacientes afectos de ESCLEROSIS LATERAL AMIOTRÓFICA.
Descriptor Portuguese: Riluzol
Descriptor French: Riluzole
Entry term(s): 2 Amino 6 trifluoromethoxybenzothiazole
2-Amino-6-trifluoromethoxybenzothiazole
PK 26124
PK-26124
PK26124
RP 54274
RP-54274
RP54274
Rilutek
Tree number(s): D02.886.675.651
D03.383.129.708.089.611
D03.633.100.185.611
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019782
Scope note: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticonvulsants
Excitatory Amino Acid Antagonists
Neuroprotective Agents
Registry Number: 7LJ087RS6F
Previous Indexing: Thiazoles (1986-1997)
Public MeSH Note: 98; RILUZOLE was indexed under THIAZOLES 1986-97
History Note: 98; use RILUZOLE (NM) 1986-97
DeCS ID: 33413
Unique ID: D019782
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2017/05/24
Riluzole - Preferred
Concept UI M0029347
Scope note A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Preferred term Riluzole
Entry term(s) 2 Amino 6 trifluoromethoxybenzothiazole
2-Amino-6-trifluoromethoxybenzothiazole
Rilutek - Narrower
Concept UI M0029348
Preferred term Rilutek
RP-54274 - Narrower
Concept UI M0373929
Preferred term RP-54274
Entry term(s) RP 54274
RP54274
PK-26124 - Narrower
Concept UI M0373930
Preferred term PK-26124
Entry term(s) PK 26124
PK26124



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