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Descriptor English: Poloxamer
Descriptor Spanish: Poloxámero
Descriptor poloxámero
Entry term(s) Pluronic
poloxámeros
Scope note: Copolímero de bloque, no iónico, de polioxietileno-polioxipropileno, de fórmula general HO(C2H4O)a(-C3H6O)b(C2H4O)aH. Está disponible en diferentes grados, de líquidos a sólidos. Se utiliza como agente emulsionante, solubilizante, surfactante y humectante en antibióticos. El poloxámero también se utiliza en pomadas, como base de supositorios y como aglutinante y para el revestimiento de tabletas (Martindale The Extra Pharmacopoeia, 31st ed).
Descriptor Portuguese: Poloxâmero
Descriptor French: Poloxamère
Entry term(s): Poloxamère 188
Poloxamère 213
Poloxamère 2930
Poloxamère 338
Poloxamère 407
Poloxamères
Tree number(s): D02.033.455.250.700.682
D05.750.741.667
D25.720.741.667
J01.637.051.720.741.667
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020442
Scope note: A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AN analyse
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
Pharm Action: Excipients
Surface-Active Agents
Registry Number: 106392-12-5
CAS Type 1 Name: alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer
DeCS ID: 33784
Unique ID: D020442
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2020/05/27
Poloxamère - Preferred
Concept UI M0030100
Preferred term Poloxamère
Poloxamère 188 - Narrower
Concept UI M0030096
Preferred term Poloxamère 188
Poloxamère 338 - Narrower
Concept UI M0030093
Preferred term Poloxamère 338
Poloxamère 407 - Narrower
Concept UI M0030099
Preferred term Poloxamère 407
Poloxamères - Broader
Concept UI M0030095
Preferred term Poloxamères
Poloxamère 213 - Narrower
Concept UI M0030097
Preferred term Poloxamère 213
Poloxamère 2930 - Narrower
Concept UI M0030098
Preferred term Poloxamère 2930



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