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Descriptor English: Tyrphostins
Descriptor Spanish: Tirfostinos
Descriptor tirfostinas
Entry term(s) tirfostina
Scope note: Familia de proteínas sintéticas inhibidoras de la tirosina cinasa. Inhiben selectivamente la autofosforilación del receptor y se utilizan en el estudio de la función de los receptores.
Descriptor Portuguese: Tirfostinas
Descriptor French: Tyrphostines
Entry term(s): Tyrphostin
Tree number(s): D02.455.426.559.389.150.795
D02.626.886
D03.633.100.857.885
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020032
Scope note: A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor function.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Enzyme Inhibitors
Previous Indexing: Benzylidene Compounds (1989-1998)
Nitriles (1989-1998)
Protein-Tyrosine Kinase/antagonists & inhibitors (1989-1998)
Public MeSH Note: 99
History Note: 99
DeCS ID: 33806
Unique ID: D020032
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/11
Revision Date: 2020/05/27
Tyrphostins - Preferred
Concept UI M0029739
Scope note A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor function.
Preferred term Tyrphostins
Entry term(s) Tyrphostin



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