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Descriptor English: I-kappa B Proteins
Descriptor Spanish: Proteínas I-kappa B
Descriptor Proteínas B I-kappa
Entry term(s) I-kappa B
Scope note: Familia de proteínas inhibidoras que se unen a las PROTEÍNAS DEL PROTOONCOGÉN REL y modulan su actividad. En el CITOPLASMA, las proteínas B I-kappa se unen al factor de transcripción NF-KAPPA B. La estimulación celular causa su disociación y traslocación del NF-kappa B activo al núcleo.
Descriptor Portuguese: Proteínas I-kappa B
Descriptor French: Protéines I-kappa B
Entry term(s): Protéines I-kappaB
Protéines IkB
Protéines Ikappa B
Tree number(s): D12.644.360.365
D12.776.260.420
D12.776.476.381
D12.776.930.326
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020672
Scope note: A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Related: Facteur de transcription NF-kappa B MeSH
I-kappa B Kinase MeSH
Protéines proto-oncogènes c-rel MeSH
DeCS ID: 34471
Unique ID: D020672
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2017/06/30
Protéines I-kappa B - Preferred
Concept UI M0328543
Preferred term Protéines I-kappa B
Entry term(s) Protéines I-kappaB
Protéines IkB
Protéines Ikappa B



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