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| Descriptor English: | CD40 Ligand | ||||||
| Descriptor Spanish: |
Ligando de CD40
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| Descriptor Portuguese: | Ligante de CD40 | ||||||
| Descriptor French: | Ligand de CD40 | ||||||
| Entry term(s): |
Antigen, CD154 Antigens, CD154 CD154 Antigen CD154 Antigens CD40L T-B Cell Activating Molecule T-Cell gp39 Antigen TNF Superfamily, Member 5 Tumor Necrosis Factor Ligand Superfamily Member 5 gp39 Antigen, T Cell gp39 Antigen, T-Cell |
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| Tree number(s): |
D12.644.276.374.750.124 D12.776.395.550.185 D12.776.467.374.750.124 D12.776.543.550.198 D23.529.374.750.124 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D023201 | ||||||
| Scope note: | A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | 147205-72-9 | ||||||
| Previous Indexing: |
Membrane Glycoproteins (1992-2000) |
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| Public MeSH Note: | 2001; CD40 LIGAND was indexed under MEMBRANE GLYCOPROTEINS 1992-2000 |
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| History Note: | 2001(2000) |
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| Related: |
CD40 Antigens
MeSH | ||||||
| DeCS ID: | 35344 | ||||||
| Unique ID: | D023201 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2001/01/01 | ||||||
| Date of Entry: | 2000/06/23 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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CD40 Ligand
- Preferred
| Concept UI |
M0200619 |
| Scope note | A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1. |
| Preferred term | CD40 Ligand |
| Entry term(s) |
Antigen, CD154 Antigens, CD154 CD154 Antigen CD154 Antigens CD40L T-B Cell Activating Molecule T-Cell gp39 Antigen TNF Superfamily, Member 5 Tumor Necrosis Factor Ligand Superfamily Member 5 gp39 Antigen, T Cell gp39 Antigen, T-Cell |
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