DeCS

Descriptor English:

Cysteamine

Descriptor Spanish:

Cisteamina

Spanish from Spain

Descriptor	cisteamina
Entry term(s)	cisteinamina mercaptamina
Scope note:	Compuesto mercaptoetilamina derivado endógenamente en la vía de degradación del ACETILCOENZIMA A. El hecho de que la cisteamina sea rápidamente transportada a los LISOSOMAS donde reacciona con la CISTINA formando disulfuro de cisteína-cisteamina ha conducido a su uso en los DEPLETORES DE CISTINA para el tratamiento de la CISTINOSIS.

Descriptor Portuguese:

Cisteamina

Descriptor French:

Mercaptamine

Entry term(s):

Bitartrate de mercaptamine
Bromhydrate de mercaptamine
Chlorhydrate de mercaptamine
Cystéamine
Mercamine
Mercaptamine (35S)
Tosilate de mercaptamine
Tosylate de mercaptamine

Tree number(s):

D02.092.471.562.369
D02.886.489.472.369

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D003543

Scope note:

A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.

Annotation:

do not confuse with CYSTAMINE

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Cystine Depleting Agents

Registry Number:

5UX2SD1KE2

CAS Type 1 Name:

Ethanethiol, 2-amino-

DeCS ID:

3562

Unique ID:

D003543

Documents indexed in the Virtual Health Library (VHL):

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