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Descriptor English: Cytarabine
Descriptor Spanish: Citarabina
Descriptor citarabina
Entry term(s) Ara C
ara-C
arabinofuranosilcitosina
arabinosilcitosina
arabinósido de citosina
aracitidina
aracitina
beta Ara C
beta-Ara C
Scope note: Análogo de nucleósido de pirimidina, que se usa primordialmente en el tratamiento de leucemias, en especial de las leucemia agudas no linfoblásticas. La citarabina es un antimetabolito antineoplásico que inhibe la síntesis de ADN. Sus acciones son específicas para la fase S del ciclo celular. También tiene propiedades antivirales e inmunosupresoras. (Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Descriptor Portuguese: Citarabina
Descriptor French: Cytarabine
Entry term(s): Chlorhydrate de cytarabine
Cytosine arabinoside
Tree number(s): D03.383.742.680.245.453
D13.570.065.300
D13.570.685.245.453
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003561
Scope note: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Antiviral Agents
Immunosuppressive Agents
Registry Number: 04079A1RDZ
CAS Type 1 Name: 2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-
Related: Décitabine MeSH
DeCS ID: 3578
Unique ID: D003561
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/02/28
Cytarabine - Preferred
Concept UI M0005564
Preferred term Cytarabine
Entry term(s) Cytosine arabinoside
Chlorhydrate de cytarabine - Narrower
Concept UI M0005565
Preferred term Chlorhydrate de cytarabine



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