DeCS

Descriptor English:

Danazol

Descriptor Spanish:

Danazol

Spanish from Spain

Descriptor	danazol
Scope note:	Esteroide sintético con actividad antigonadotrópica y antiestrogénica, que actúa como supresor en la adenohipófisis inhibiendo la salida de las gonadotropinas de la hipófisis. Posee algunas propiedades androgénicas. El danazol se ha utilizado en el tratamiento de la endometriosis y de algunos trastornos mamarios benignos.

Descriptor Portuguese:

Danazol

Descriptor French:

Danazol

Tree number(s):

D04.210.500.745.432.235

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D003613

Scope note:

A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Estrogen Antagonists

Registry Number:

N29QWW3BUO

CAS Type 1 Name:

Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol, (17alpha)-

DeCS ID:

3632

Unique ID:

D003613

NLM Classification:

WP 522