DeCS

Descriptor English:

Dapsone

Descriptor Spanish:

Dapsona

Spanish from Spain

Descriptor	dapsona
Entry term(s)	diaminodifenilsulfona sulfonildianilina
Scope note:	Sulfona activa frente a una amplia variedad de bacterias, pero que se emplea principalmente por sus acciones contra el MYCOBACTERIUM LEPRAE. Su mecanismo de acción probablemente es similar al de las SULFONAMIDAS, que inhiben la síntesis de ácido fólico en los organismos susceptibles. También se usa junto con la PIRIMETAMINA en el tratamineto de la malaria. (Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

Descriptor Portuguese:

Dapsona

Descriptor French:

Dapsone

Entry term(s):

4,4'-Diaminodiphénylsulfone

Tree number(s):

D02.886.590.263

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D003622

Scope note:

A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Anti-Infective Agents
Antimalarials
Folic Acid Antagonists
Leprostatic Agents

Registry Number:

8W5C518302

DeCS ID:

3641

Unique ID:

D003622

NLM Classification:

QV 259

Documents indexed in the Virtual Health Library (VHL):

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