You have selected the view in French
Descriptor English: | Debrisoquin | ||||
Descriptor Spanish: |
Debrisoquina
| ||||
Descriptor Portuguese: | Debrisoquina | ||||
Descriptor French: | Débrisoquine | ||||
Tree number(s): |
D03.633.100.531.205 |
||||
RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D003647 | ||||
Scope note: | An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism. |
||||
Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
||||
Pharm Action: |
Antihypertensive Agents Sympatholytics Adrenergic Agents |
||||
Registry Number: | X31CDK040E | ||||
CAS Type 1 Name: | 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro- | ||||
DeCS ID: | 3665 | ||||
Unique ID: | D003647 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1991/01/01 | ||||
Date of Entry: | 1999/01/01 | ||||
Revision Date: | 2016/05/28 |
-
-
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés hétérocycliques [D03]Composés hétérocycliques
|
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey