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Descriptor English: Ajmaline
Descriptor Spanish: Ajmalina
Descriptor ajmalina
Scope note: Alcaloide que se encuentra en la raíz de RAUWOLFIA SERPENTINA, entre otras fuentes vegetales. Es un agente antiarrítmico de clase 1a que, aparentemente, actúa cambiando la forma y el umbral de los potenciales de acción cardiacos.
Descriptor Portuguese: Ajmalina
Descriptor French: Ajmaline
Entry term(s): Chlorhydrate d'ajmaline
Tree number(s): D03.132.436.681.077
D03.633.100.473.402.681.077
D03.633.100.496.500.500.681.077
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000404
Scope note: An alkaloid found in the root of RAUWOLFIA SERPENTINA, among other plant sources. It is a class 1-A antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anti-Arrhythmia Agents
Voltage-Gated Sodium Channel Blockers
Registry Number: 1PON08459R
CAS Type 1 Name: Ajmalan-17,21-diol, (17R,21alpha)-
DeCS ID: 407
Unique ID: D000404
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Ajmaline - Preferred
Concept UI M0000613
Preferred term Ajmaline
Chlorhydrate d'ajmaline - Narrower
Concept UI M0584206
Preferred term Chlorhydrate d'ajmaline



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