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Descriptor English: Dihydropteridine Reductase
Descriptor Spanish: Dihidropteridina Reductasa
Descriptor dihidropteridina reductasa
Scope note: Enzima que cataliza la reducción de 6,7-dihidropteridina a 5,6,7,8-tetrahidropteridina en presencia de NADP+. Los defectos en la enzima son causa de la FENILCETONURIA II. Anteriormente se clasificó como EC 1.6.99.7.
Descriptor Portuguese: Di-Hidropteridina Redutase
Descriptor French: Dihydropteridine reductase
Entry term(s): 6,7 Dihydropteridine Reductase
6,7-Dihydropteridine Reductase
Reductase, 6,7-Dihydropteridine
Reductase, Dihydropteridine
Tree number(s): D08.811.682.662.582.361
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004093
Scope note: An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Phenylketonurias
Registry Number: EC 1.5.1.34
CAS Type 1 Name: NAD(P)H:6,7-dihydropteridine oxidoreductase
Previous Indexing: NADH, NADPH Oxidoreductases (1973-1974)
Pteridines (1973-1974)
Public MeSH Note: 91; was see under NADH, NADPH OXIDOREDUCTASES 1975-90
History Note: 91(75); was see under NADH, NADPH OXIDOREDUCTASES 1975-90
DeCS ID: 4133
Unique ID: D004093
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/27
Revision Date: 2015/06/22
Dihydropteridine Reductase - Preferred
Concept UI M0006412
Scope note An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
Preferred term Dihydropteridine Reductase
Entry term(s) 6,7 Dihydropteridine Reductase
6,7-Dihydropteridine Reductase
Reductase, 6,7-Dihydropteridine
Reductase, Dihydropteridine



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