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Descriptor English: DNA-Directed DNA Polymerase
Descriptor Spanish: ADN Polimerasa Dirigida por ADN
Descriptor ADN polimerasa dirigida por ADN
Entry term(s) ADN polimerasa N3
ADN polimerasas
ADN polimerasas dependientes de ADN
ADN-polimerasa
DNA polimerasa N3
DNA polimerasas
DNA polimerasas DNA-dependientes
DNA polimerasas dependientes de DNA
Scope note: ADN polimerasas dependientes de ADN, que se encuentran en bacterias y en células de animales y de vegetales. Durante el proceso de replicación, estas enzimas catalizan la adición de residuos de desoxirribonucleótidos en el extremo de una hebra de ADN, en presencia de ADN como molde-cebador. También poseen actividad de exonucleasa y por ello actúan en la reparación del ADN.
Descriptor Portuguese: DNA Polimerase Dirigida por DNA
Descriptor French: DNA-directed DNA polymerase
Entry term(s): DNA Dependent DNA Polymerases
DNA Directed DNA Polymerase
DNA Polymerase
DNA Polymerase N3
DNA Polymerase, DNA-Directed
DNA Polymerases
DNA Polymerases, DNA-Dependent
DNA-Dependent DNA Polymerases
Polymerase N3, DNA
Polymerase, DNA
Polymerase, DNA-Directed DNA
Polymerases, DNA
Polymerases, DNA-Dependent DNA
Tree number(s): D08.811.913.696.445.308.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004259
Scope note: DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
Annotation: general; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Nucleic Acid Synthesis Inhibitors
Registry Number: EC 2.7.7.7
CAS Type 1 Name: Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Previous Indexing: DNA Nucleotidyltransferases (1968-1976)
Public MeSH Note: 98; see DNA POLYMERASES 1977-97, for DNA POLYMERASE see DNA NUCLEOTIDYLTRANSFERASES 1973-76, see DNA NUCLEOTIDYLTRANSFERASE 1968-72
History Note: 98(68); for DNA POLYMERASE use DNA NUCLEOTIDYLTRANSFERASES 1968-76
DeCS ID: 4326
Unique ID: D004259
NLM Classification: QU 141
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1976/04/19
Revision Date: 2020/05/27
DNA-Directed DNA Polymerase - Preferred
Concept UI M0006665
Scope note DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
Preferred term DNA-Directed DNA Polymerase
Entry term(s) DNA Dependent DNA Polymerases
DNA Directed DNA Polymerase
DNA Polymerase
DNA Polymerase, DNA-Directed
DNA Polymerases
DNA Polymerases, DNA-Dependent
DNA-Dependent DNA Polymerases
Polymerase, DNA
Polymerase, DNA-Directed DNA
Polymerases, DNA
Polymerases, DNA-Dependent DNA
DNA Polymerase N3 - Narrower
Concept UI M0006664
Preferred term DNA Polymerase N3
Entry term(s) Polymerase N3, DNA



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