Descriptor English: | DNA Repair | ||||||
Descriptor Spanish: |
Reparación del ADN
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Descriptor Portuguese: | Reparo do DNA | ||||||
Descriptor French: | Réparation de l'ADN | ||||||
Entry term(s): |
Base Excision Repair Base Excision Repairs Excision Repair Excision Repair, Base Excision Repair, Nucleotide Excision Repairs Nucleotide Excision Repair Nucleotide Excision Repairs Repair, Base Excision Repair, Excision Repairs, Base Excision |
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Tree number(s): |
G02.111.222 G05.219 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D004260 | ||||||
Scope note: | The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light. |
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Annotation: | coord IM with specific DNA (IM) |
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Allowable Qualifiers: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
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Previous Indexing: |
DNA (1966-1970) DNA/biosynthesis (1966-1970) |
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Public MeSH Note: | 74 |
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History Note: | 74(71) |
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Related: |
Pyrimidine Dimers
MeSH | ||||||
DeCS ID: | 4328 | ||||||
Unique ID: | D004260 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1974/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2016/06/17 |
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PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena -
PHENOMENA AND PROCESSES
Genetic Phenomena [G05]Genetic Phenomena
|
DNA Repair
- Preferred
Excision Repair
- Narrower
Nucleotide Excision Repair
- Narrower
Base Excision Repair
- Narrower
Concept UI |
M0006666 |
Scope note | The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light. |
Preferred term | DNA Repair |
Concept UI |
M0006667 |
Preferred term | Excision Repair |
Entry term(s) |
Excision Repairs Repair, Excision |
Concept UI |
M0006668 |
Preferred term | Nucleotide Excision Repair |
Entry term(s) |
Excision Repair, Nucleotide Nucleotide Excision Repairs |
Concept UI |
M0448966 |
Preferred term | Base Excision Repair |
Entry term(s) |
Base Excision Repairs Excision Repair, Base Repair, Base Excision Repairs, Base Excision |
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