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Descriptor English: Estramustine
Descriptor Spanish: Estramustina
Descriptor estramustina
Entry term(s) estramustinfosfato
Scope note: Mostaza nitrogenada unida al estradiol, generalmente como fosfato; utilizada en el tratamiento de neoplasias de próstata; tiene también propiedades protectoras frente a la radiación.
Descriptor Portuguese: Estramustina
Descriptor French: Estramustine
Entry term(s): Leo-275
Leo275
NSC-89199
NSC89199
Phosphate d'estramustine
Phosphate d'estramustine de sodium
Phosphate d'estramustine sodique
Tree number(s): D02.455.526.728.650.275
D04.210.500.365.415.248.320
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004961
Scope note: A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents, Alkylating
Antineoplastic Agents, Hormonal
Registry Number: 35LT29625A
CAS Type 1 Name: Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-(bis(2-chloroethyl)carbamate)
DeCS ID: 5053
Unique ID: D004961
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Estramustine - Preferred
Concept UI M0007783
Preferred term Estramustine
Phosphate d'estramustine sodique - Narrower
Concept UI M0007784
Preferred term Phosphate d'estramustine sodique
Entry term(s) Phosphate d'estramustine de sodium
Leo-275 - Narrower
Concept UI M0351238
Preferred term Leo-275
Entry term(s) Leo275
NSC-89199 - Narrower
Concept UI M0351240
Preferred term NSC-89199
Entry term(s) NSC89199
Phosphate d'estramustine - Narrower
Concept UI M0007785
Preferred term Phosphate d'estramustine



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