DeCS

Descriptor English:

Ethambutol

Descriptor Spanish:

Etambutol

Spanish from Spain

Descriptor	etambutol
Scope note:	Agente antituberculoso que inhibe la transferencia de ácidos micólicos a la pared celular del bacilo de la tuberculosis. También puede inhibir la síntesis de la espermidina en las micobacterias. Generalmente su acción es bactericida y el ffármaco puede atravesar las membranas de las células humanas para ejercer su efecto letal. (Smith and Reynard, Textbook of Pharmacology, 1992, p863).

Descriptor Portuguese:

Etambutol

Descriptor French:

Éthambutol

Tree number(s):

D02.092.782.258.368.265

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D004977

Scope note:

An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antitubercular Agents

Registry Number:

8G167061QZ

CAS Type 1 Name:

1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, (S-(R*,R*))-

DeCS ID:

5069

Unique ID:

D004977

NLM Classification:

QV 268