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Descriptor English: Clusterin
Descriptor Spanish: Clusterina
Descriptor clusterina
Scope note: Glicoproteína heterodimérica, muy estable, que se expresa en muy diversos trastornos fisiológicos graves, como el CÁNCER, la APOPTOSIS y algunas TRASTORNOS NEUROLÓGICOS. La clusterina se expresa de forma ubicua y parece funcionar como una CHAPERONA MOLECULAR secretada.
Descriptor Portuguese: Clusterina
Descriptor French: Clusterine
Entry term(s): ApoJ Protein
Apolipoprotein J
Complement Associated Protein SP 40,40
Complement Lysis Inhibitor
Complement-Associated Protein SP-40,40
Ionizing Radiation Induced Protein 8
Ionizing Radiation-Induced Protein-8
MAC393 Antigen
Radiation-Induced Protein-8, Ionizing
SGP 2 Protein
SGP-2 Protein
SP 40,40 Protein
SP-40,40, Complement-Associated Protein
Sulfated Glycoprotein 2
Sulfated Glycoprotein-2
TRPM 2 Protein
TRPM-2 Protein
Testosterone Repressed Prostate Message 2 Protein
Testosterone-Repressed Prostate Message-2 Protein
X Ray Inducible Protein 8
X-Ray-Inducible Protein 8
XIP8 Protein
Tree number(s): D12.776.395.207
D12.776.580.215
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051152
Scope note: A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; CLUSTERIN was indexed under GLYCOPROTEINS & MOLECULAR CHAPERONES 1981-2005, & under SALIVARY PROTEINS 1980
History Note: 2006(1980)
DeCS ID: 51074
Unique ID: D051152
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/06/28
Clusterin - Preferred
Concept UI M0082230
Scope note A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
Preferred term Clusterin
Entry term(s) ApoJ Protein
Apolipoprotein J
Complement Associated Protein SP 40,40
Complement Lysis Inhibitor
Complement-Associated Protein SP-40,40
Ionizing Radiation Induced Protein 8
Ionizing Radiation-Induced Protein-8
MAC393 Antigen
Radiation-Induced Protein-8, Ionizing
SGP 2 Protein
SGP-2 Protein
SP 40,40 Protein
SP-40,40, Complement-Associated Protein
Sulfated Glycoprotein 2
Sulfated Glycoprotein-2
TRPM 2 Protein
TRPM-2 Protein
Testosterone Repressed Prostate Message 2 Protein
Testosterone-Repressed Prostate Message-2 Protein
X Ray Inducible Protein 8
X-Ray-Inducible Protein 8
XIP8 Protein



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