Search
Descriptor English: Gene Fusion
Descriptor Spanish: Fusión Génica
Descriptor fusión génica
Scope note: Es la RECOMBINACIÓN GENÉTICA de partes de dos o más GENES, que da como resultado un gen con regiones reguladoras diferentes o adicionales, o un nuevo producto génico quimérico. La FUSIÓN ONCÓGENA incluye un ONCOGÉN como al menos uno de los genes acompañantes en la fusión. Dichas fusiones génicas, observadas con frecuencia en las células neoplásicas, se transcriben a través de PROTEÍNAS ONCOGÉNICAS DE FUSIÓN. La FUSIÓN GÉNICA ARTIFICIAL se realiza in vitro mediante técnicas de ADN RECOMBINANTE.
Descriptor Portuguese: Fusão Gênica
Descriptor French: Fusion de gènes
Entry term(s): Fusion, Gene
Fusions, Gene
Gene Fusions
Tree number(s): G05.728.385
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050939
Scope note: The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.
Annotation: ARTIFICIAL GENE FUSION is also available
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Artificial Gene Fusion (1998-2005)
Public MeSH Note: 2006
History Note: 2006
Related: Artificial Gene Fusion MeSH
Mutant Chimeric Proteins MeSH
DeCS ID: 51239
Unique ID: D050939
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/06/17
Gene Fusion - Preferred
Concept UI M0478722
Scope note The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.
Preferred term Gene Fusion
Entry term(s) Fusion, Gene
Fusions, Gene
Gene Fusions



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey