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Descriptor English: Exfoliatins
Descriptor Spanish: Exfoliatinas
Descriptor exfoliatinas
Entry term(s) dermolisisnas
epidermolisinas
toxinas epidermolíticas
toxinas exfoliantes
Scope note: Exotoxinas proteicas del fago tipo II de Staphylococcus aureus, que produce necrólisis epidérmica. Son proteínas de 26.000 a 32.000 de peso molecular. Producen una enfermedad conocida como piel escaldada, síndrome de Lyell o Ritter, enfermedad epidérmica exfoliativa, necrólisis epidérmica tóxica, etc.
Descriptor Portuguese: Exfoliatinas
Descriptor French: Exfoliatines
Entry term(s): Dermolysins
Epidermolysins
Epidermolytic Toxins
Exfoliatin Toxin A
Exfoliative Toxin B
Exfoliative Toxin, Staphylococcal
Exfoliative Toxins
Staphylococcal Exfoliative Toxin
Toxin A, Exfoliatin
Toxin B, Exfoliative
Toxin, Staphylococcal Exfoliative
Toxins, Epidermolytic
Toxins, Exfoliative
Tree number(s): D12.776.097.293
D23.946.123.353
D23.946.350.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005083
Scope note: Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative disease, toxic epidermal necrolysis, etc.
Annotation: /antag permitted but consider also ANTITOXINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Dermotoxins
Previous Indexing: Bacterial Proteins (1966-1976)
Bacterial Toxins (1977)
Staphylococcal Infections (1966-1977)
Toxins (1966-1976)
Public MeSH Note: 91; was see under BACTERIAL TOXINS 1978-90
History Note: 91(78); was see under BACTERIAL TOXINS 1978-90
DeCS ID: 5181
Unique ID: D005083
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/22
Revision Date: 2018/06/29
Exfoliatins - Preferred
Concept UI M0008012
Scope note Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative disease, toxic epidermal necrolysis, etc.
Preferred term Exfoliatins
Entry term(s) Epidermolysins
Exfoliative Toxin, Staphylococcal
Staphylococcal Exfoliative Toxin
Toxin, Staphylococcal Exfoliative
Exfoliative Toxins - Broader
Concept UI M0008014
Preferred term Exfoliative Toxins
Entry term(s) Toxins, Exfoliative
Exfoliatin Toxin A - Narrower
Concept UI M0008011
Preferred term Exfoliatin Toxin A
Entry term(s) Toxin A, Exfoliatin
Exfoliative Toxin B - Narrower
Concept UI M0008013
Preferred term Exfoliative Toxin B
Entry term(s) Toxin B, Exfoliative
Dermolysins - Related but not broader or narrower
Concept UI M0008009
Preferred term Dermolysins
Epidermolytic Toxins - Broader
Concept UI M0008010
Preferred term Epidermolytic Toxins
Entry term(s) Toxins, Epidermolytic



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