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Descriptor English: Brugada Syndrome
Descriptor Spanish: Síndrome de Brugada
Descriptor síndrome de brugada
Scope note: Defecto autosómico dominante de la conducción cardiaca que se caracteriza por un segmento ST anormal en las derivaciones V1-V3 del ELECTROCARDIOGRAMA, semejante a un BLOQUEO DE RAMA derecha, riesgo elevado de TAQUICARDIA VENTRICULAR o FIBRILACIÓN VENTRICULAR, EPISODIOS DE SÍNCOPE y posible muerte súbita. Este síndrome se asocia a mutaciones del gen codificador de la subunidad alfa del CANAL DE SODIO cardiaco.
Descriptor Portuguese: Síndrome de Brugada
Descriptor French: Syndrome de Brugada
Entry term(s): Brugada ECG Pattern
Brugada Syndrome 1
Brugada Type ECG Pattern
ECG Pattern, Brugada
Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome
Sudden Unexplained Death Syndrome
Sudden Unexplained Nocturnal Death Syndrome
Sudden Unexplained Nocturnal Death Syndrome (SUNDS)
Tree number(s): C14.280.067.322
C14.280.123.250
C16.320.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053840
Scope note: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Arrhythmia (1996-2006)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52136
Unique ID: D053840
NLM Classification: WG 330
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2019/05/17
Brugada Syndrome - Preferred
Concept UI M0496826
Scope note An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.
Preferred term Brugada Syndrome
Entry term(s) Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome
Sudden Unexplained Death Syndrome
Sudden Unexplained Nocturnal Death Syndrome
Sudden Unexplained Nocturnal Death Syndrome (SUNDS)
Brugada ECG Pattern - Related but not broader or narrower
Concept UI M0496827
Preferred term Brugada ECG Pattern
Entry term(s) Brugada Type ECG Pattern
ECG Pattern, Brugada
Brugada Syndrome 1 - Narrower
Concept UI M000648999
Preferred term Brugada Syndrome 1



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