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Descriptor English: 2-Pyridinylmethylsulfinylbenzimidazoles
Descriptor Spanish: 2-Piridinilmetilsulfinilbencimidazoles
Descriptor 2-piridinilmetilsulfinilbencimidazoles
Scope note: Compuestos que contienen bencimidazol unido a 2-metilpiridina vía un enlace sulfóxido. Varios de los compuestos de esta clase son AGENTES ANTIULCEROSOS que actúan mediante inhibición de la ATPASA HIDRÓGENO-POTASIO de la BOMBA DE PROTONES de las CÉLULAS PARIETALES GÁSTRICAS.
Descriptor Portuguese: 2-Piridinilmetilsulfinilbenzimidazóis
Descriptor French: (Pyridin-2-ylméthyl)sulfinyl-1H-benzimidazoles
Entry term(s): 2 Methylpyridine 2 Benzimidazole Sulfoxides
2 Pyridinylmethylsulfinyl 2 Benzimidazoles
2 Pyridinylmethylsulfinylbenzimidazoles
2-Benzimidazole Sulfoxides, 2-Methylpyridine
2-Methylpyridine 2-Benzimidazole Sulfoxides
2-Pyridinylmethylsulfinyl-2-Benzimidazoles
Benzimidazole Methylpyridine Sulfoxides
Methylpyridine Sulfoxides, Benzimidazole
Sulfoxides, 2-Methylpyridine 2-Benzimidazole
Sulfoxides, Benzimidazole Methylpyridine
Timoprazole Derivatives
Timoprazoles
Tree number(s): D02.886.640.074
D03.383.725.024
D03.633.100.103.034
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053799
Scope note: Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52172
Unique ID: D053799
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/05/27
2-Pyridinylmethylsulfinylbenzimidazoles - Preferred
Concept UI M0496552
Scope note Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
Preferred term 2-Pyridinylmethylsulfinylbenzimidazoles
Entry term(s) 2 Pyridinylmethylsulfinylbenzimidazoles
Benzimidazole Methylpyridine Sulfoxides
Methylpyridine Sulfoxides, Benzimidazole
Sulfoxides, Benzimidazole Methylpyridine
Timoprazole Derivatives - Narrower
Concept UI M0496553
Preferred term Timoprazole Derivatives
Entry term(s) 2 Methylpyridine 2 Benzimidazole Sulfoxides
2 Pyridinylmethylsulfinyl 2 Benzimidazoles
2-Benzimidazole Sulfoxides, 2-Methylpyridine
2-Methylpyridine 2-Benzimidazole Sulfoxides
2-Pyridinylmethylsulfinyl-2-Benzimidazoles
Sulfoxides, 2-Methylpyridine 2-Benzimidazole
Timoprazoles



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