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Descriptor English: Myeloblastin
Descriptor Spanish: Mieloblastina
Descriptor mieloblastina
Entry term(s) autoantígeno de Wegener
proteinasa 3 de los neutrófilos
Scope note: Serina proteasa derivada de los leucocitos polimorfonucleares que degrada proteínas como la ELASTINA, la FIBRONECTINA, la LAMININA, la VITRONECTINA y el COLÁGENO. Recibe su nombre por su capacidad de controlar el crecimiento y la diferenciación de las células mieloides.
Descriptor Portuguese: Mieloblastina
Descriptor French: Myéloblastine
Entry term(s): Antigen, C-ANCA
Autoantigen, Wegener
Azurophil Granule Protein 7
C ANCA Antigen
C-ANCA Antigen
Human Myeloblastin
Leukocyte Proteinase 3
Myeloblastin, Human
N Proteinase 4
N-Proteinase 4
Neutrophil Proteinase 3
Neutrophil Proteinase 3, Human
Neutrophil Proteinase 4
PRTN3 Gene Protein
Protein, PRTN3 Gene
Proteinase 3
Proteinase 3, Leukocyte
Proteinase 3, Neutrophil
Proteinase 4, Neutrophil
Wegener Autoantigen
Tree number(s): D08.811.277.656.300.760.530
D08.811.277.656.959.350.530
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053146
Scope note: A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.76
Previous Indexing: Serine Endopeptidases (1988-2006)
Wegener Granulomatosis (1990-2006)
Public MeSH Note: 2007
History Note: 2007
Related: Granulomatosis with Polyangiitis MeSH
DeCS ID: 52245
Unique ID: D053146
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2009/07/06
Myeloblastin - Preferred
Concept UI M0161951
Scope note A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
Preferred term Myeloblastin
Entry term(s) Antigen, C-ANCA
Autoantigen, Wegener
Azurophil Granule Protein 7
C ANCA Antigen
C-ANCA Antigen
Human Myeloblastin
Leukocyte Proteinase 3
Myeloblastin, Human
N Proteinase 4
N-Proteinase 4
Neutrophil Proteinase 3
Neutrophil Proteinase 3, Human
Neutrophil Proteinase 4
PRTN3 Gene Protein
Protein, PRTN3 Gene
Proteinase 3
Proteinase 3, Leukocyte
Proteinase 3, Neutrophil
Proteinase 4, Neutrophil
Wegener Autoantigen



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