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Descriptor English: CRADD Signaling Adaptor Protein
Descriptor Spanish: Proteína Adaptadora de Señalización CRADD
Descriptor proteína adaptadora de señalización CRADD
Entry term(s) adaptador de caspasas y Rip con proteína de dominio de muerte
proteína adaptadora de señalización RAIDD
Scope note: Proteína adaptadora de la señalización del receptor del dominio de muerte que desempeña un papel en la señalización de la activación de CASPASAS INICIADORAS tales como la CASPASA 2. Contiene un dominio de muerte que es específico de las serina-treonina cinasas RIP y un dominio de unión a caspasas que se une a CASPASAS y las activa, como la CASPASA 2.
Descriptor Portuguese: Proteína Adaptadora de Sinalização CRADD
Descriptor French: Protéine adaptatrice de signalisation CRADD
Entry term(s): Caspase and Rip Adaptor with Death Domain Protein
RAIDD Signaling Adaptor Protein
RIP Associated Protein With a Death Domain
RIP-Associated Protein With a Death Domain
Tree number(s): D12.644.360.024.131.186
D12.644.360.024.285.050
D12.644.360.024.500.050
D12.644.360.075.358.186
D12.644.360.075.421.050
D12.776.157.057.006.186
D12.776.157.057.018.050
D12.776.157.057.500.050
D12.776.476.024.139.186
D12.776.476.024.320.050
D12.776.476.024.500.050
D12.776.476.075.358.186
D12.776.476.075.421.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053420
Scope note: A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Adaptor Proteins, Signal Transducing (2005-2006)
Proteins (1997-2004)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52305
Unique ID: D053420
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
CRADD Signaling Adaptor Protein - Preferred
Concept UI M0492988
Scope note A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.
Preferred term CRADD Signaling Adaptor Protein
Entry term(s) Caspase and Rip Adaptor with Death Domain Protein
RAIDD Signaling Adaptor Protein
RIP Associated Protein With a Death Domain
RIP-Associated Protein With a Death Domain



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