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Descriptor English: Ghrelin
Descriptor Spanish: Ghrelina
Descriptor ghrelina
Entry term(s) ghrelin
grelina
Scope note: Péptido acilado, orexígeno, de 28 aminoácidos que es un ligando de los RECEPTORES SECRETAGOGOS DE LA HORMONA DEL CRECIMIENTO. La grelina se expresa ampliamente, pero sobre todo en el estómago de los adultos. La grelina actúa centralmente estimulando la secreción de la hormona del crecimiento y la ingesta de alimento, y periféricamente regulando la homeostasis de energía. Su gran proteína precursora, la hormona reguladora del apetito o péptido relacionado con la motilina, contiene grelina y obestatina.
Descriptor Portuguese: Grelina
Descriptor French: Ghréline
Entry term(s): Appetite Regulating Hormone
Appetite-Regulating Hormone
GHRL Protein
Gastric MLTRP
Ghrelin Obestatin Preprohormone
Ghrelin Precursor
Ghrelin-Obestatin Preprohormone
Motilin Related Peptide
Motilin Related Peptide Precursor
Motilin-Related Peptide
Motilin-Related Peptide Precursor
Obestatin
Peptide Precursor, Motilin-Related
PpMTLRP
Ppghrelin
Precursor, Ghrelin
Precursor, Motilin-Related Peptide
Tree number(s): D06.472.699.301
D12.644.548.322
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054439
Scope note: A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Growth Hormone-Releasing Hormone (2000-2007)
Peptide Hormones (1999-2007)
Public MeSH Note: 2008; GHRELIN was indexed under PEPTIDE HORMONES 2000-2007
History Note: 2008 (2000)
DeCS ID: 52658
Unique ID: D054439
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Ghrelin - Preferred
Concept UI M0354824
Scope note A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
Preferred term Ghrelin
GHRL Protein - Narrower
Concept UI M0504910
Preferred term GHRL Protein
Entry term(s) Ghrelin Obestatin Preprohormone
Ghrelin Precursor
Ghrelin-Obestatin Preprohormone
Motilin Related Peptide Precursor
Motilin-Related Peptide Precursor
Peptide Precursor, Motilin-Related
PpMTLRP
Ppghrelin
Precursor, Ghrelin
Precursor, Motilin-Related Peptide
Obestatin - Related but not broader or narrower
Concept UI M0504911
Preferred term Obestatin
Appetite-Regulating Hormone - Narrower
Concept UI M0368310
Preferred term Appetite-Regulating Hormone
Entry term(s) Appetite Regulating Hormone
Gastric MLTRP
Motilin Related Peptide
Motilin-Related Peptide



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