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Descriptor English: Urocortins
Descriptor Spanish: Urocortinas
Descriptor urocortinas
Entry term(s) urocortina
Scope note: Neuropéptidos de unos 40 aminoácidos que son estructuralmente similares al FACTOR LIBERADOR DE CORTICOTROPINA (CRF). A diferencia del CRF, que actúa sobre todo a través de RECEPTORES DE CRF de tipo 1, las urocortinas señalizan preferentemente a través de los receptores de CRF de tipo 2. Las urocortinas tienen amplia distribución tisular, de los peces a los mamíferos, y desempeñan diversas funciones. En los mamíferos, las urocortinas pueden inhibir la ingestión de alimentos, retrasan el vaciamiento gástrico y disminuyen el edema inducido por el calor.
Descriptor Portuguese: Urocortinas
Descriptor French: Urocortines
Entry term(s): Ucn (Urocortines)
Ucn I
Ucn II
Ucn III
Urocortine
Urocortine I
Urocortine II
Urocortine III
Urocortine-1
Urocortine-2
Urocortine-3
Tree number(s): D06.472.699.857
D12.644.400.837
D12.644.548.887
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054832
Scope note: Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
DeCS ID: 52659
Unique ID: D054832
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Urocortines - Preferred
Concept UI M0254327
Preferred term Urocortines
Entry term(s) Ucn (Urocortines)
Urocortine-3 - Narrower
Concept UI M0394061
Preferred term Urocortine-3
Entry term(s) Ucn III
Urocortine III
Urocortine-1 - Narrower
Concept UI M0508138
Preferred term Urocortine-1
Entry term(s) Ucn I
Urocortine
Urocortine I
Urocortine-2 - Narrower
Concept UI M0397626
Preferred term Urocortine-2
Entry term(s) Ucn II
Urocortine II



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