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Descriptor English: Cathepsin K
Descriptor Spanish: Catepsina K
Descriptor catepsina K
Scope note: Cisteína proteasa altamente expresada en los OSTEOCLASTOS que desempeña un papel fundamental en la REABSORCIÓN ÓSEA, como una potente enzima que degrada la MATRIZ EXTRACELULAR. 
Descriptor Portuguese: Catepsina K
Descriptor French: Cathepsine K
Tree number(s): D08.811.277.656.224.405
D08.811.277.656.262.500.156
D08.811.277.656.300.200.156
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056657
Scope note: A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.
Annotation: Cathepsin X, an obsolete multi-meaning term appearing in older literature goes here or at CATHEPSIN Z: check text; Cathepsin O and Cathepsin O2 in older literature go here.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Registry Number: EC 3.4.22.38
DeCS ID: 53600
Unique ID: D056657
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Cathepsine K - Preferred
Concept UI M0528260
Preferred term Cathepsine K



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