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Descriptor English: Islet Amyloid Polypeptide
Descriptor Spanish: Polipéptido Amiloide de los Islotes Pancreáticos
Descriptor polipéptido amiloide de los islotes
Scope note: Hormona de las células beta pancreáticas que es cosegregado con la INSULINA. Exhibe un efecto anoréxico sobre el metabolismo de los nutrientes al inhibir la secreción de ácido gástrico, la evacuación gástrica y la secreción postprandial de GLUCAGÓN. El polipéptido amiloide de los islotes puede plegarse en FIBRILLAS AMILOIDES que se han encontrado como constituyente principal de los DEPÓSITOS DE AMILOIDE del páncreas.
Descriptor Portuguese: Polipeptídeo Amiloide das Ilhotas Pancreáticas
Descriptor French: Polypeptide amyloïde des ilots
Entry term(s): Amlintide
Amylin
Amylin, Pancreatic
Amyloid Polypeptide, Insulinoma
Amyloid Polypeptide, Islet
IAPP Precursor
IAPP Protein
Insulinoma Amyloid Polypeptide
Insulinoma Amyloid Polypeptide Precursor
Islet Amyloid Polypeptide Precursor
Pancreatic Amylin
Polypeptide, Insulinoma Amyloid
Polypeptide, Islet Amyloid
Tree number(s): D06.472.699.587.334
D12.644.548.586.234
D12.776.049.407.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D058228
Scope note: A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Appetite Depressants
Amylin Receptor Agonists
Public MeSH Note: 2011; AMYLIN now ISLET AMYLOID POLYPEPTIDE was indexed under AMYLOID 1987-2010
History Note: 2011
DeCS ID: 54057
Unique ID: D058228
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Islet Amyloid Polypeptide - Preferred
Concept UI M0541516
Scope note A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
Preferred term Islet Amyloid Polypeptide
Entry term(s) Amlintide
Amylin
Amylin, Pancreatic
Amyloid Polypeptide, Insulinoma
Amyloid Polypeptide, Islet
IAPP Protein
Insulinoma Amyloid Polypeptide
Pancreatic Amylin
Polypeptide, Insulinoma Amyloid
Polypeptide, Islet Amyloid
Islet Amyloid Polypeptide Precursor - Narrower
Concept UI M0164943
Preferred term Islet Amyloid Polypeptide Precursor
Entry term(s) IAPP Precursor
Insulinoma Amyloid Polypeptide Precursor



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