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Descriptor English: CRISPR-Associated Proteins
Descriptor Spanish: Proteínas Asociadas a CRISPR
Descriptor proteínas asociadas a CRISPR
Scope note: Componentes proteicos de los SISTEMAS CRISPR-CAS, de defensa antiviral en ARCHAEA y BACTERIAS. Son proteínas que realizan diversas funciones durante la creación y expansión de las MATRICES CRISPR, la captura de ESPACIADORES CRISPR, la biogénesis de ARN INTERFERENTE PEQUEÑO (crispr o crARN) y el marcado y silenciamiento de virus y plásmidos invasores. Comprenden ADN HELICASAS, PROTEÍNAS DE UNIÓN A ARN, ENDONUCLEASAS y ARN y ADN POLIMERASAS.
Descriptor Portuguese: Proteínas Associadas a CRISPR
Descriptor French: Protéines associées aux CRISPR
Entry term(s): CASCADE Proteins, CRISPR Associated
CASCADE Proteins, CRISPR-Associated
CRISPR Associated Complex for Antiviral Defense Proteins
CRISPR Associated Protein Complex Proteins
CRISPR Associated Proteins
CRISPR-Associated CASCADE Proteins
CRISPR-Associated Complex for Antiviral Defense Proteins
CRISPR-Associated Protein Complex Proteins
Proteins, CRISPR-Associated
Proteins, Repeat-Associated Mysterious
Repeat Associated Mysterious Proteins
Repeat-Associated Mysterious Proteins
Tree number(s): D12.776.212
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064130
Scope note: Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2014
History Note: 2014
Related: Clustered Regularly Interspaced Short Palindromic Repeats MeSH
DeCS ID: 55330
Unique ID: D064130
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
CRISPR-Associated Proteins - Preferred
Concept UI M0579775
Scope note Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.
Preferred term CRISPR-Associated Proteins
Entry term(s) CRISPR Associated Proteins
Proteins, CRISPR-Associated
CRISPR-Associated Protein Complex Proteins - Narrower
Concept UI M0579776
Scope note Proteins in RIBONUCLEOPROTEIN assemblies of CRISPR-CAS SYSTEMS that function in targeting DNA of invading viruses and plasmids.
Preferred term CRISPR-Associated Protein Complex Proteins
Entry term(s) CASCADE Proteins, CRISPR Associated
CASCADE Proteins, CRISPR-Associated
CRISPR Associated Complex for Antiviral Defense Proteins
CRISPR Associated Protein Complex Proteins
CRISPR-Associated CASCADE Proteins
CRISPR-Associated Complex for Antiviral Defense Proteins
Repeat-Associated Mysterious Proteins - Narrower
Concept UI M0579785
Scope note A large superfamily of CRISPR-ASSOCIATED PROTEINS that contain at least one RNA recognition motif.
Preferred term Repeat-Associated Mysterious Proteins
Entry term(s) Proteins, Repeat-Associated Mysterious
Repeat Associated Mysterious Proteins



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