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| Descriptor English: | Protein Aggregation, Pathological | ||||||
| Descriptor Spanish: |
Agregación Patológica de Proteínas
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| Descriptor Portuguese: | Agregação Patológica de Proteínas | ||||||
| Descriptor French: | Agrégation pathologique de protéines | ||||||
| Entry term(s): |
Aggregation, Pathological Protein Pathological Protein Aggregation |
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| Tree number(s): |
C23.550.770 G02.111.675 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D066263 | ||||||
| Scope note: | A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS. |
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| Allowable Qualifiers: |
BL blood CF cerebrospinal fluid CI chemically induced CL classification CN congenital CO complications DG diagnostic imaging DH diet therapy DI diagnosis DT drug therapy EC economics EH ethnology EM embryology EN enzymology EP epidemiology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PA pathology PC prevention & control PP physiopathology PS parasitology PX psychology RH rehabilitation RT radiotherapy SU surgery TH therapy UR urine VE veterinary VI virology |
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| Public MeSH Note: | 2015 |
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| History Note: | 2015 |
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| Related: |
Protein Aggregates
MeSH | ||||||
| DeCS ID: | 55596 | ||||||
| Unique ID: | D066263 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2015/01/01 | ||||||
| Date of Entry: | 2014/06/26 | ||||||
| Revision Date: | 2020/02/05 |
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PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena
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Protein Aggregation, Pathological
- Preferred
| Concept UI |
M0593510 |
| Scope note | A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS. |
| Preferred term | Protein Aggregation, Pathological |
| Entry term(s) |
Aggregation, Pathological Protein Pathological Protein Aggregation |
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