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Descriptor English: Cobicistat
Descriptor Spanish: Cobicistat
Descriptor cobicistat
Scope note: Derivado del carbamato y del tiazol que funciona como un INHIBIDOR DEL CITOCROMO P-450 CYP3A para aumentar la concentración de FÁRMACOS ANTI-VIH, con la que se utiliza en combinación, para el tratamiento de las INFECCIONES POR VIH.
Descriptor Portuguese: Cobicistat
Descriptor French: Cobicistat
Entry term(s): 9350, GS
GS 9350
GS-9350
GS9350
Tybost
Tree number(s): D02.241.081.251.203
D02.886.675.182
D03.383.129.708.189
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069547
Scope note: A carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-HIV Agents
Cytochrome P-450 CYP3A Inhibitors
Registry Number: LW2E03M5PG
Public MeSH Note: 2016; COBICISTAT was indexed under CARBAMATES and THIAZOLES 2011-2015
History Note: 2016 (2011)
DeCS ID: 55886
Unique ID: D000069547
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/28
Cobicistat - Preferred
Concept UI M0558562
Scope note A carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS.
Preferred term Cobicistat
Tybost - Narrower
Concept UI M000606069
Preferred term Tybost
GS 9350 - Narrower
Concept UI M0558563
Preferred term GS 9350
Entry term(s) 9350, GS
GS-9350
GS9350



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