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Descriptor English: Cinacalcet
Descriptor Spanish: Cinacalcet
Descriptor cinacalcet
Entry term(s) AMG 073
AMG073
KRN 1493
Sensipar
clorhidrato de cinacalcet
hidrocloruro de (alfaR) alfa-metil-N-(3-(3-(trifluorometil)fenil)propil)-1-naftalenmetanamina
Scope note: Derivado del naftaleno y CALCIMIMÉTICO que aumenta la sensibilidad de los receptores sensibles al calcio de las GLÁNDULAS PARATIROIDES al calcio sérico. Esta acción reduce la secreción de la hormona paratiroidea y disminuye el calcio sérico en el tratamiento de las ENFERMEDADES DE LAS PARATIROIDES.
Descriptor Portuguese: Cinacalcete
Descriptor French: Cinacalcet
Entry term(s): AMG 073
AMG073
Alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride
Cinacalcet Hydrochloride
KRN 1493
Sensipar
Tree number(s): D02.455.426.559.847.638.183
D04.615.638.183
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069449
Scope note:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Calcium-Regulating Hormones and Agents
Calcimimetic Agents
Registry Number: UAZ6V7728S
Public MeSH Note: 2019; was CINACALCET HYDROCHLORIDE 2016-2018; CINACALCET HYDROCHLORIDE was indexed under NAPHTHALENES 2003-2015
History Note: 2019 (2003)
DeCS ID: 55894
Unique ID: D000069449
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/09
Revision Date: 2018/05/22
Cinacalcet - Preferred
Concept UI M000616896
Preferred term Cinacalcet
Cinacalcet Hydrochloride - Narrower
Concept UI M0452505
Scope note A naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in the treatment of PARATHYROID DISEASES.
Preferred term Cinacalcet Hydrochloride
Entry term(s) Alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride
Sensipar - Narrower
Concept UI M0462190
Preferred term Sensipar
AMG 073 - Narrower
Concept UI M0452507
Preferred term AMG 073
Entry term(s) AMG073
KRN 1493



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