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Descriptor English: Rilpivirine
Descriptor Spanish: Rilpivirina
Descriptor rilpivirina
Scope note: Derivado de la diarilpirimidina e INHIBIDOR DE LA TRANSCRIPTASA INVERSA con actividad antiviral contra el VIH-1 que es usado en el tratamiento de las INFECCIONES POR VIH. También se utiliza en combinación con otros FÁRMACOS ANTI-VIH, ya que la RESISTENCIA A ANTIVIRALES surge rápidamente cuando se utiliza solo.
Descriptor Portuguese: Rilpivirina
Descriptor French: Rilpivirine
Entry term(s): Chlorhydrate de rilpivirine
R-278474
R278474
TMC-278
TMC278
Tree number(s): D02.626.809
D03.383.742.755
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068696
Scope note: A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Reverse Transcriptase Inhibitors
Anti-HIV Agents
Registry Number: FI96A8X663
DeCS ID: 55897
Unique ID: D000068696
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/31
Rilpivirine - Preferred
Concept UI M0482137
Preferred term Rilpivirine
Chlorhydrate de rilpivirine - Narrower
Concept UI M000603537
Preferred term Chlorhydrate de rilpivirine
R-278474 - Narrower
Concept UI M0482138
Preferred term R-278474
Entry term(s) R278474
TMC-278 - Narrower
Concept UI M0493524
Preferred term TMC-278
Entry term(s) TMC278



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