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Descriptor English: Perilipin-1
Descriptor Spanish: Perilipina-1
Descriptor perilipina 1
Entry term(s) perilipina
perilipina A
perilipina B
proteína PERI
proteína Plin
proteína perilipina
proteína perilipina A
proteína perilipina B
Scope note: Proteína de las gotas lipídicas expresada principalmente por los ADIPOCITOS del TEJIDO ADIPOSO BLANCO y del TEJIDO ADIPOSO PARDO. Se colocaliza con los MACRÓFAGOS y las CÉLULAS ESPUMOSAS de las lesiones ateroscleróticas y estabiliza las GOTAS LIPÍDICAS inhibiendo la LIPASA SENSIBLE A HORMONAS. También puede proteger a los TRIGLICÉRIDOS de la hidrólisis dentro de la MEMBRANA PLASMÁTICA y modular la actividad de la COLESTEROL ÉSTER HIDROLASA.
Descriptor Portuguese: Perilipina-1
Descriptor French: Périlipine-1
Entry term(s): Protéine PERI
Protéine Plin
Protéine périlipine
Protéine périlipine A
Protéine périlipine B
Périlipine A
Périlipine B
Tree number(s): D12.776.157.464.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000070778
Scope note: A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
DeCS ID: 56571
Unique ID: D000070778
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/01/15
Périlipine-1 - Preferred
Concept UI M0188823
Preferred term Périlipine-1
Entry term(s) Protéine PERI
Protéine Plin
Protéine périlipine
Protéine périlipine A
Protéine périlipine B
Périlipine A
Périlipine B



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