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Descriptor English: Promyelocytic Leukemia Protein
Descriptor Spanish: Proteína de la Leucemia Promielocítica
Descriptor proteína de la leucemia promielocítica
Entry term(s) proteína RNF71
proteína TRIM19
Scope note: PROTEÍNA DE MOTIVOS TRIPARTITOS que contiene tres DEDOS DE ZINC, incluido un DOMINIO RING FINGER, en el extremo N-terminal. El empalme alternativo del gen PML da lugar a varias isoformas nucleares y una isoforma citoplasmática. La mayoría de isoformas nucleares se localizan en estructuras subnucleares (cuerpos nucleares PML) que están alteradas en las células de la LEUCEMIA PROMIELOCÍTICA AGUDA.
Descriptor Portuguese: Proteína da Leucemia Promielocítica
Descriptor French: Protéine de la leucémie promyélocytaire
Entry term(s): Protéine RNF71
Protéine TRIM19
Tree number(s): D12.776.624.776.654
D12.776.660.745
D12.776.930.713
D12.776.934.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071156
Scope note: A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
DeCS ID: 56647
Unique ID: D000071156
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/02/26
Protéine de la leucémie promyélocytaire - Preferred
Concept UI M000613226
Preferred term Protéine de la leucémie promyélocytaire
Entry term(s) Protéine RNF71
Protéine TRIM19



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