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Descriptor English: Donepezil
Descriptor Spanish: Donepezilo
Descriptor donepezilo
Entry term(s) Aricept
E 2020
E-2020
E2020
Eranz
hidrocloruro de 1-bencil-4-((5,6-dimetoxi-1-indanon)-2-il)metilpiperidina
hidrocloruro de donepezil
oxalato de donepezilo trihidratado
Scope note: Derivado de indano y piperidina que actúa como inhibidor selectivo y reversible de la ACETILCOLINESTERASA. El donepezilo presenta una selectividad alta por el sistema nervioso central y se usa en el tratamiento de la DEMENCIA de leve a moderada en la ENFERMEDAD DE ALZHEIMER.
Descriptor Portuguese: Donepezila
Descriptor French: Donépézil
Entry term(s): Chlorhydrate de donépézil
E-2020
E2020
Tree number(s): D02.455.426.559.847.486.487.280
D03.383.621.238
D04.615.486.487.280
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077265
Scope note: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Cholinesterase Inhibitors
Nootropic Agents
Registry Number: 8SSC91326P
CAS Type 1 Name: 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-
DeCS ID: 57568
Unique ID: D000077265
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03
Donépézil - Preferred
Concept UI M0206795
Preferred term Donépézil
E-2020 - Narrower
Concept UI M0206796
Preferred term E-2020
Entry term(s) E2020
Chlorhydrate de donépézil - Narrower
Concept UI M0206791
Preferred term Chlorhydrate de donépézil



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