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Descriptor English: Letrozole
Descriptor Spanish: Letrozol
Descriptor letrozol
Entry term(s) 4,4'-(1H-1,2,4-triazol-1-il-metilen)-bis(benzonitrilo)
CGS 20267
CGS-20267
CGS20267
Femara
Scope note: Derivado de triazol y benzonitrilo que es un inhibidor no esteroideo selectivo de la aromatasa, similar al ANASTROZOL. Se usa en el tratamiento del cáncer de mama localmente avanzado o metastásico en mujeres posmenopáusicas.
Descriptor Portuguese: Letrozol
Descriptor French: Létrozole
Entry term(s): CGS-20267
Tree number(s): D02.626.300
D03.383.129.799.638
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077289
Scope note: A triazole and benzonitrile derivative that is a selective non-steroidal aromatase inhibitor, similar to ANASTROZOLE. It is used in the treatment of metastatic or locally advanced breast cancer in postmenopausal women.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents
Aromatase Inhibitors
Registry Number: 7LKK855W8I
CAS Type 1 Name: Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-
DeCS ID: 57590
Unique ID: D000077289
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Létrozole - Preferred
Concept UI M000640349
Preferred term Létrozole
CGS-20267 - Narrower
Concept UI M0184833
Preferred term CGS-20267



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