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Descriptor English: Cidofovir
Descriptor Spanish: Cidofovir
Descriptor cidofovir
Entry term(s) 1-((3-hidroxi-2-fosfonilmetoxi)propil)citosina
1-(3-hidroxi-2-fosfonilmetoxipropil)citosina
GS 504
GS-504
GS504
HPMPC
Vistide
cidofovir anhidro
cidofovir sódico
isómero (+-) del cidofovir
isómero (R) del cidofovir
sal sódica de cidofovir
Scope note: Fosfonato nucleosídico acíclico que actúa como inhibidor competitivo de las ADN-polimerasas víricas. Se usa en el tratamiento de la RETINITIS causada por INFECCIONES POR CITOMEGALOVIRUS y también puede ser útil para tratar las INFECCIONES POR HERPESVIRUS.
Descriptor Portuguese: Cidofovir
Descriptor French: Cidofovir
Entry term(s): 1-((3-Hydroxy-2-phosphonylmethoxy)propyl)cytosine
1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine
Cidofovir Anhydrous
Cidofovir Sodium
Cidofovir, (+-)-isomer
Cidofovir, (R)-isomer
Cidofovir, Sodium Salt
GS 504
GS-504
GS504
HPMPC
Vistide
Tree number(s): D02.705.429.437
D03.383.742.698.421.216
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077404
Scope note: An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiviral Agents
Enzyme Inhibitors
Registry Number: JIL713Q00N
CAS Type 1 Name: Phosphonic acid, (((1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy)methyl)-
Public MeSH Note: 2019; CIDOFOVIR was indexed under CYTOSINE/analogs & derivatives 1989-2018; under ORGANOPHOSPHONATES 2005-2018; and under ORGANOPHOSPHORUS COMPOUNDS 1989-2004
History Note: 2019 (1989)
DeCS ID: 57632
Unique ID: D000077404
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03
Cidofovir - Preferred
Concept UI M0164905
Scope note An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.
Preferred term Cidofovir
Entry term(s) HPMPC
GS 504 - Narrower
Concept UI M0164901
Preferred term GS 504
Entry term(s) GS-504
GS504
Cidofovir, Sodium Salt - Narrower
Concept UI M0324124
Preferred term Cidofovir, Sodium Salt
Entry term(s) Cidofovir Sodium
Cidofovir, (R)-isomer - Narrower
Concept UI M0324126
Preferred term Cidofovir, (R)-isomer
Cidofovir Anhydrous - Narrower
Concept UI M0585102
Preferred term Cidofovir Anhydrous
1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine - Related but not broader or narrower
Concept UI M000640704
Preferred term 1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine
Entry term(s) 1-((3-Hydroxy-2-phosphonylmethoxy)propyl)cytosine
Vistide - Narrower
Concept UI M0164904
Preferred term Vistide
Cidofovir, (+-)-isomer - Narrower
Concept UI M0324125
Preferred term Cidofovir, (+-)-isomer



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