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Descriptor English: Vemurafenib
Descriptor Spanish: Vemurafenib
Descriptor vemurafenib
Entry term(s) PLX 4032
PLX4032
R05185426
RG 7204
RG-7204
RG7204
Zelboraf
Scope note: Compuesto de indol y sulfonamida e inhibidor de las PROTEÍNAS PROTOONCOGÉNICAS B-RAF que se usa para el tratamiento del MELANOMA irresecable o metastásico.
Descriptor Portuguese: Vemurafenib
Descriptor French: Vémurafénib
Entry term(s): PLX-4032
PLX4032
R05185426
RG-7204
RG7204
Tree number(s): D02.065.884.919
D02.886.590.700.919
D03.633.100.473.936
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077484
Scope note: An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic MELANOMA.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number: 207SMY3FQT
CAS Type 1 Name: 1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-
DeCS ID: 57657
Unique ID: D000077484
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Vémurafénib - Preferred
Concept UI M0558887
Preferred term Vémurafénib
PLX4032 - Narrower
Concept UI M0548744
Preferred term PLX4032
Entry term(s) PLX-4032
RG7204 - Narrower
Concept UI M000623499
Preferred term RG7204
Entry term(s) RG-7204
R05185426 - Narrower
Concept UI M000623498
Preferred term R05185426



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