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Descriptor English:

Eplerenone

Descriptor Spanish:

Eplerenona

Spanish from Spain

Descriptor	eplerenona
Entry term(s)	9,11-epoxi-7-(metoxicarbonil)-3-Oxo-17-pregn-4-eno-21,17-carbolactona Inspra
Scope note:	Derivado de espironolactona y antagonista selectivo de los RECEPTORES DE MINERALOCORTICOIDES que se usa en el tratamiento de la HIPERTENSIÓN y en el tratamiento de la INSUFICIENCIA CARDÍACA CONGESTIVA después de un INFARTO DE MIOCARDIO.

Descriptor Portuguese:

Eplerenona

Descriptor French:

Éplérénone

Tree number(s):

D02.540.383
D04.210.500.745.745.329

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000077545

Scope note:

A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Mineralocorticoid Receptor Antagonists
Antihypertensive Agents

Registry Number:

6995V82D0B

CAS Type 1 Name:

Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-

DeCS ID:

57670

Unique ID:

D000077545

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2019/01/01

Date of Entry:

2018/07/09

Revision Date:

2018/04/09