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Descriptor English: Crizotinib
Descriptor Spanish: Crizotinib
Descriptor crizotinib
Entry term(s) PF 02341066
PF 2341066
PF-02341066
PF-2341066
PF02341066
PF2341066
Xalkori
Scope note: Derivado piperidínico y aminopiridínico que actúa como inhibidor de RECEPTORES PROTEÍNA-TIROSINA CINASAS, tales como la CINASA DEL LINFOMA ANAPLÁSICO (ALK) y el RECEPTOR DEL FACTOR DE CRECIMIENTO HEPATOCÍTICO (HGFR, c-Met). Se usa en el tratamiento del CARCINOMA PULMONAR NO MICROCÍTICO.
Descriptor Portuguese: Crizotinibe
Descriptor French: Crizotinib
Entry term(s): PF-02341066
PF-2341066
PF02341066
PF2341066
Tree number(s): D03.383.621.154
D03.383.725.050.263
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077547
Scope note: A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number: 53AH36668S
CAS Type 1 Name: 2-Pyridinamine, 3-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-
DeCS ID: 57672
Unique ID: D000077547
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Crizotinib - Preferred
Concept UI M0553416
Preferred term Crizotinib
PF-02341066 - Narrower
Concept UI M0549737
Preferred term PF-02341066
Entry term(s) PF-2341066
PF02341066
PF2341066



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