DeCS

Descriptor English:

Aprepitant

Descriptor Spanish:

Aprepitant

Spanish from Spain

Descriptor	aprepitant
Entry term(s)	(1-(3,5-bis(trifluorometil)fenil)etoxi)-3-(fluoro)fenil-4-(3-oxo-1,2,4-triazol-5-il)metilmorfolina (2R)-(1R)-3,5-bis(trifluorometilfenil)etoxi)-(3S)-(4-fluoro)fenil-4-(3-(5-oxo-1H,4H-1,2,4-triazol)metil-morfolina Emend L 754,030 L 754030 L-754,030 L-754030 L754,030 L754030 MK 0517 MK 0869 MK 869 MK-0517 MK-0869 MK-869 MK0517 MK0869 MK869
Scope note:	Antagonista morfolínico de los receptores de la neurocinina-1 (NK1) que se usa en el tratamiento de las náuseas y vómitos causados por la FARMACOTERAPIA y para la prevención de las NÁUSEAS Y VÓMITOS POSOPERATORIOS.

Descriptor Portuguese:

Aprepitanto

Descriptor French:

Aprépitant

Entry term(s):

L-754030
L754030
MK-0517
MK-0869
MK-869
MK0517
MK0869
MK869

Tree number(s):

D03.383.533.640.125

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000077608

Scope note:

A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antiemetics
Neurokinin-1 Receptor Antagonists

Registry Number:

1NF15YR6UY

CAS Type 1 Name:

3H-1,2,4-Triazol-3-one, 5-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,4-dihydro-

DeCS ID:

57711

Unique ID:

D000077608

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents