DeCS

Descriptor English:

Afatinib

Descriptor Spanish:

Afatinib

Spanish from Spain

Descriptor	afatinib
Entry term(s)	(2E)-N-(4-(3-cloro-4-fluoroanilino)-7-(((3S)-oxolan-3-il)oxi)quinoxazolin-6-il)-4-(dimetilamino)but-2-enamida BIBW 2992 BIBW 2992 MA2 BIBW 2992MA2 BIBW-2992 BIBW-2992-MA2 BIBW-2992MA2 BIBW2992 BIBW2992 MA2 Gilotrif dimaleato de afatinib maleato de afatinib
Scope note:	Derivado de quinazolina y butenamida que actúa como inhibidor de la tirosina-cinasa de los receptores del factor de crecimiento epidérmico (RECEPTORES ERBB) y se usa en el tratamiento del CARCINOMA PULMONAR NO MICROCÍTICO metastásico.

Descriptor Portuguese:

Afatinib

Descriptor French:

Afatinib

Entry term(s):

BIBW-2992
BIBW-2992-MA2
BIBW-2992MA2
BIBW2992
BIBW2992-MA2
Dimaléate d'afatinib

Tree number(s):

D02.065.132
D03.633.100.786.188

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000077716

Scope note:

A quinazoline and butenamide derivative that acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in the treatment of metastatic NON-SMALL CELL LUNG CANCER.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antineoplastic Agents
Protein Kinase Inhibitors

Registry Number:

41UD74L59M

CAS Type 1 Name:

2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-, (2E)-

DeCS ID:

57729

Unique ID:

D000077716

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents