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Descriptor English: Diterpene Alkaloids
Descriptor Spanish: Alcaloides Diterpénicos
Descriptor alcaloides diterpénicos
Entry term(s) alcaloide de diterpeno
Scope note: Derivados alcaloides de los diterpenos (p. ej., KAURANOS; CLERODANOS) que a menudo contienen estructuras con puentes de nitrógeno. Según el número de átomos de carbono de su estructura central, estos alcaloides pueden dividirse en los siguientes tipos: diterpenos de 18 C, diterpenos de 19 C, diterpenos de 20 C y bis-diterpenos. Están presentes principalmente en RANUNCULACEAE (p. ej., ACONITUM y DELPHINIUM) y pueden poseer acciones analgésicas, antiarrítmicas y antiinflamatorias. Algunos son cardiotóxicos por el bloqueo de los CANALES DEL CALCIO TIPO L.
Descriptor Portuguese: Alcaloides Diterpenos
Descriptor French: Alcaloïdes diterpéniques
Entry term(s): Alkaloid, Diterpene
Alkaloids, Diterpene
Diterpene Alkaloid
Tree number(s): D02.455.849.291.184
D03.132.301
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077743
Scope note: Alkaloids derived from diterpenes (e.g., KAURANES; CLERODANES) often containing the nitrogen bridge structures. These alkaloids may be divided into C18-, C19-, C20- and bis-diterpene types depending on the number of carbon atoms in their central framework. They are found most often in RANUNCULACEAE (e.g., ACONITUM and DELPHINIUM) and may possess analgesic, antiarrhythmic and anti-inflammatory activities. Some are cardiotoxic by blocking L-TYPE CALCIUM CHANNELS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Alkaloids (1963-2018)
Diterpenes (1963-2018)
Public MeSH Note: 2019
History Note: 2019
DeCS ID: 57742
Unique ID: D000077743
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2020/05/27
Diterpene Alkaloids - Preferred
Concept UI M000641422
Scope note Alkaloids derived from diterpenes (e.g., KAURANES; CLERODANES) often containing the nitrogen bridge structures. These alkaloids may be divided into C18-, C19-, C20- and bis-diterpene types depending on the number of carbon atoms in their central framework. They are found most often in RANUNCULACEAE (e.g., ACONITUM and DELPHINIUM) and may possess analgesic, antiarrhythmic and anti-inflammatory activities. Some are cardiotoxic by blocking L-TYPE CALCIUM CHANNELS.
Preferred term Diterpene Alkaloids
Entry term(s) Alkaloid, Diterpene
Alkaloids, Diterpene
Diterpene Alkaloid



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