DeCS

Descriptor English:

Amifampridine

Descriptor Spanish:

Amifampridina

Spanish from Spain

Descriptor	amifampridina
Entry term(s)	3,4 diaminopiridina 3,4-diaminopiridina Firdapse Ruzurgi fosfato de amifampridina
Scope note:	Derivado de la 4-aminopiridina que actúa como bloqueador de los CANALES DEL POTASIO para aumentar la liberación de ACETILCOLINA por las terminaciones nerviosas. Se usa en el tratamiento de los SÍNDROMES MIASTÉNICOS CONGÉNITOS.

Descriptor Portuguese:

Amifampridina

Descriptor French:

Amifampridine

Entry term(s):

Phosphate d'amifampridine

Tree number(s):

D02.092.080.060.500
D03.383.725.050.060.500

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000077770

Scope note:

4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Neuromuscular Agents
Potassium Channel Blockers

Registry Number:

RU4S6E2G0J

CAS Type 1 Name:

3,4-Pyridinediamine

DeCS ID:

57749

Unique ID:

D000077770

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents