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Descriptor English:

Hydrochlorothiazide

Descriptor Spanish:

Hidroclorotiazida

Spanish from Spain

Descriptor	hidroclorotiacida
Entry term(s)	hidroclorotiazida
Scope note:	Diurético tiacídico considerado frecuentemente como el prototipo de esta clase. Reduce la absorción de electrólitos en los túbulos renales. Esto se sigue de aumento de la excreción de agua y electrólitos como sodio, potasio, cloro y magnesio. Se ha utilizado en el tratamiento de procesos graves como edemas, hipertensión, diabetes insípida e hipoparatiroidismo.

Descriptor Portuguese:

Hidroclorotiazida

Descriptor French:

Hydrochlorothiazide

Tree number(s):

D02.886.590.700.135.261.476
D02.886.655.500.261.476
D03.633.100.174.261.476

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D006852

Scope note:

A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antihypertensive Agents
Diuretics
Sodium Chloride Symporter Inhibitors

Registry Number:

0J48LPH2TH

CAS Type 1 Name:

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide

DeCS ID:

7005

Unique ID:

D006852

NLM Classification:

QV 160