| Descriptor English: | Amyotrophic Lateral Sclerosis | ||||||
| Descriptor Spanish: |
Esclerosis Amiotrófica Lateral
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| Descriptor Portuguese: | Esclerose Amiotrófica Lateral | ||||||
| Descriptor French: | Sclérose latérale amyotrophique | ||||||
| Entry term(s): |
ALS - Amyotrophic Lateral Sclerosis ALS Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis Parkinsonism Dementia Complex 1 Amyotrophic Lateral Sclerosis With Dementia Amyotrophic Lateral Sclerosis, Guam Form Amyotrophic Lateral Sclerosis, Parkinsonism Dementia Complex of Guam Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia Complex of Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex 1 Charcot Disease Dementia With Amyotrophic Lateral Sclerosis Disease, Guam Disease, Lou-Gehrigs Gehrig Disease Gehrig's Disease Gehrigs Disease Guam Disease Guam Form of Amyotrophic Lateral Sclerosis Lou Gehrig Disease Lou Gehrig's Disease Lou-Gehrigs Disease Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Amyotrophic Lateral |
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| Tree number(s): |
C10.228.854.139 C10.574.562.250 C10.574.950.050 C10.668.467.250 C18.452.845.800.050 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000690 | ||||||
| Scope note: | A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) |
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| Allowable Qualifiers: |
BL blood CF cerebrospinal fluid CI chemically induced CL classification CN congenital CO complications DG diagnostic imaging DH diet therapy DI diagnosis DT drug therapy EC economics EH ethnology EM embryology EN enzymology EP epidemiology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PA pathology PC prevention & control PP physiopathology PS parasitology PX psychology RH rehabilitation RT radiotherapy SU surgery TH therapy UR urine VE veterinary VI virology |
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| Entry Version: | ALS |
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| DeCS ID: | 704 | ||||||
| Unique ID: | D000690 | ||||||
| NLM Classification: | WE 552 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2019/04/29 |
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Amyotrophic Lateral Sclerosis
- Preferred
Amyotrophic Lateral Sclerosis, Guam Form
- Narrower
Amyotrophic Lateral Sclerosis With Dementia
- Related but not broader or narrower
| Concept UI |
M0001056 |
| Scope note | A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) |
| Preferred term | Amyotrophic Lateral Sclerosis |
| Entry term(s) |
ALS - Amyotrophic Lateral Sclerosis ALS Amyotrophic Lateral Sclerosis Charcot Disease Disease, Lou-Gehrigs Gehrig Disease Gehrig's Disease Gehrigs Disease Lou Gehrig Disease Lou Gehrig's Disease Lou-Gehrigs Disease Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Amyotrophic Lateral |
| Concept UI |
M0334022 |
| Preferred term | Amyotrophic Lateral Sclerosis, Guam Form |
| Entry term(s) |
Amyotrophic Lateral Sclerosis Parkinsonism Dementia Complex 1 Amyotrophic Lateral Sclerosis, Parkinsonism Dementia Complex of Guam Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia Complex of Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex 1 Disease, Guam Guam Disease Guam Form of Amyotrophic Lateral Sclerosis |
| Concept UI |
M0334021 |
| Preferred term | Amyotrophic Lateral Sclerosis With Dementia |
| Entry term(s) |
Dementia With Amyotrophic Lateral Sclerosis |
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