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Descriptor English: Hydroxyzine
Descriptor Spanish: Hidroxizina
Descriptor hidroxicina
Scope note: Antagonista de los receptores H1 de histamina que es efectivo en el tratamiento de la urticaria crónica, dermatítis y prurito mediado por histamina. A diferencia de su metabolito CETIRICINA, este compuesto causa somnolencia. Asimismo, es efectivo como antiemético, como ansiolítico y relajante, y como sedante.
Descriptor Portuguese: Hidroxizina
Descriptor French: Hydroxyzine
Entry term(s): Chlorhydrate d'hydroxyzine
Dichlorhydrate d'hydroxyzine
Pamoate d'hydroxyzine
Tree number(s): D03.383.606.515
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006919
Scope note: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antipruritics
Histamine H1 Antagonists
Registry Number: 30S50YM8OG
CAS Type 1 Name: Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-
DeCS ID: 7098
Unique ID: D006919
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Hydroxyzine - Preferred
Concept UI M0010792
Preferred term Hydroxyzine
Dichlorhydrate d'hydroxyzine - Narrower
Concept UI M0331417
Preferred term Dichlorhydrate d'hydroxyzine
Pamoate d'hydroxyzine - Narrower
Concept UI M0331416
Preferred term Pamoate d'hydroxyzine
Chlorhydrate d'hydroxyzine - Narrower
Concept UI M0010795
Preferred term Chlorhydrate d'hydroxyzine



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