DeCS

Descriptor English:

Kainic Acid

Descriptor Spanish:

Ácido Kaínico

Spanish from Spain

Descriptor	ácido kaínico
Entry term(s)	kainato ácido digénico
Scope note:	Ácido (2S-(2 alfa,3 beta,4 beta))-2-carboxi-4-(1-metiletenil)-3-pirrolidinacético. Ascaricida que se obtiene a partir del alga roja Digenea simplex. Se trata de un potente agonista de aminoácidos excitatorios en determinados tipos de receptores de aminoácidos excitatorios y se ha utilizado para discriminar tipos de receptores. Al igual que muchos agonistas de amonoácidos excitatorios, puede causar neurotoxicidad, por lo que se ha utilizado experimentalmente con este fin.

Descriptor Portuguese:

Ácido Caínico

Descriptor French:

Acide kaïnique

Entry term(s):

Kaïnate

Tree number(s):

D03.383.773.400

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D007608

Scope note:

(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.

Annotation:

an antinematodal agent & excitatory amino acid agonist

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antinematodal Agents
Excitatory Amino Acid Agonists

Registry Number:

SIV03811UC

CAS Type 1 Name:

3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-

Récepteurs kaïnate MeSH

DeCS ID:

7777

Unique ID:

D007608

Documents indexed in the Virtual Health Library (VHL):